Presence of HBsAg in the serum is indicative of active HBV infection, either acute or chronic.
Antibodies against hepatitis B core antigen (anti-HBc) are only detected in individuals who have been infected with HBV. As with other antibodies generated in response to infection IgM is present during the initial immune response, this is replaced over time by IgG antibodies.
Anti-HBc IgG is produced from around 14 weeks after exposure, in the absence of anti-HBc IgM it may indicate cleared or chronic HBV infection.
Presence of hepatitis C antibodies indicates exposure to the virus, if detected a viral RNA load is required to determine whether there is active infection.
Persistence of viral RNA in the bloodstream more than six months after exposure (or acute illness if symptoms develop) indicates chronic infection.
Antibodies against hepatitis B surface antigen (anti-HBs) indicate a vaccinated individual (the vaccine is based upon the HBsAg protein) or previous infection with HBV (seroconversion to produce anti-HBs in the setting of HBV infection indicates the infection has been cleared).
Anti-HBc IgM is detectable between six and 32 weeks after exposure and indicates acute HBV infection.
Acute hepatitis C infection is asymptomatic in 60-70% of cases, infection is chronic in around 85% of individuals.
Antibodies against hepatitis B core antigen (anti-HBc) are only detected in individuals who have been infected with HBV. As with other antibodies generated in response to infection IgM is present during the initial immune response, this is replaced over time by IgG antibodies.
Anti-HBc IgG is produced from around 14 weeks after exposure, in the absence of anti-HBc IgM it may indicate cleared or chronic HBV infection.
Presence of hepatitis C antibodies indicates exposure to the virus, if detected a viral RNA load is required to determine whether there is active infection.
Persistence of viral RNA in the bloodstream more than six months after exposure (or acute illness if symptoms develop) indicates chronic infection.
Antibodies against hepatitis B surface antigen (anti-HBs) indicate a vaccinated individual (the vaccine is based upon the HBsAg protein) or previous infection with HBV (seroconversion to produce anti-HBs in the setting of HBV infection indicates the infection has been cleared).
Anti-HBc IgM is detectable between six and 32 weeks after exposure and indicates acute HBV infection.
Acute hepatitis C infection is asymptomatic in 60-70% of cases, infection is chronic in around 85% of individuals.
No comments:
Post a Comment